The best face cream for pimples and dark spots treatment should contain ingredients that will help fight off these blemishes by increasing the amount of collagen and elastin the skin has. You see, as we age, our bodies produce less collagen and elastin, and the only way to replace them is by producing more of the proteins they naturally make. However, the same ingredients that make this process easier can also cause your dark spots to get worse. Ingredients like retinol, or vitamin A, can cause the production of collagen and elastin to stop completely, which allows your skin to revert to its earlier state. In fact, some ingredients like azelaic acid even cause a reduction in melanin, which can make your complexion even darker.